Reversible male subfertility due to hyperthyroidism.

Reversible male subfertility due to hyperthyroidism.

A 26-year-old man with a one-year history of attempted conception was referred to a male subfertility clinic. Two previous semen analyses had disclosed oligospermia with sperm counts of 11 x 109/1 on both occasions (figure). He had had classical symptoms of thyrotoxicosis for five years and 18 months earlier had been investigated for palpitations. Examination showed a diffuse goitre, tremor, an...

Economic strategies in modern male subfertility treatment.

Reversible agranulocytosis due to meprobamate.

A 52 year old man admitted to hospital in a toxic state, was found to have agranulocytosis, which recovered when an analgesic containing meprobamate was stopped. The patient was known to have had similar symptoms 9 months previously when the drug was first used, thereby demonstrating an idiosyncratic reaction to meprobamate.

Reversible Fluoxetine-Induced Hyperthyroidism: A Case Report

BACKGROUND Selective serotonin reuptake inhibitors (SSRIs) are typically used as antidepressants. Clinically significant SSRI-induced thyroid dysfunction is rare. CASE We report a case of hyperthyroidism induced by fluoxetine in a female patient with major depressive disorder. Her thyroid profiles indicated hyperthyroidism after a 10-week treatment with fluoxetine and were restored after disc...

Reversible male infertility due to sulphasalazine: studies in man and rat.

Sulphasalazine treatment for inflammatory bowel disease in man causes oligospermia, reduced sperm motility and an increased proportion of abnormal forms. On withdrawal of sulphasalazine these effects are found to be reversible and 15 pregnancies occurred at a median of 2.5 months after stopping sulphasalazine therapy. Seminal plasma concentrations of acid phosphatase fructose and PGE2 as well a...